Endocrine Abstracts

Case history: A 30-year-old Afrocaribbean lady with a history of Graves’ thyrotoxicosis (2012) and subsequent thyroidectomy (2013) presented to the antenatal clinic in January 2020 at 9+6w gestation. Medication included levothyroxine 125 mg daily. She had a history of neonatal thyrotoxicosis in her first pregnancy in 2017 which required carbimazole therapy due to fetal tachycardia.Investigations: At booking, thyroid function tests (TFTs) showed a TS...

The amount of radioactivity given to patients undergoing ablation for remnant tissue in thyroid cancer at our centre has been greatly reduced to 1100 MBq I-131 in recent years, prompting a review of practice. An extensive risk assessment, focusing particularly on radiation exposure to the public during the patient’s commute home was conducted and found patients could now be discharged safely on the day of treatment. Owing to these findings and audit showing 86% of patient...

Background: Although MRI remains the investigation of choice for pituitary imaging, it does not provide information about the ‘functionality’ of lesions (e.g. residual adenoma vs post-surgical scar tissue), and cannot reliably identify all microadenomas. These limitations are of particular relevance in acromegaly where clinical and biochemical evidence of disease activity mandates (further) treatment.Methods: We hypothesised that i) imaging wit...